Recently, it is pointed out that the Sea of Okhotsk and the surrounding environment (the Pan- Okhotsk region) is very sensitive to global warming.The amount of sea ice production in the Sea of Okhotsk greatly decreases by the global warming, resulting in a considerable decrease in dense water production.This dense water is transported from the northwestern continental region in the Sea of Okhotsk to the Oyashio region through the typical water circulation system;hence, the dense water plays an important role as the transporter to the region of nutrients,especially iron originated from the Amur River.Therefore, the global warming will weaken the biological productivity of this sea area due to the large decrease of sea ice production.This article calls for the establishment of an observation and research network for the Pan- Okhotsk region to enable global warming forcasts.