Remarkable progress has been made in genome sequencing technology and a wealth of data on gene function has been collected. In addition, by combining genome editing technologies that have been developed in recent years, there is a possibility we can breed and selectively breed fish species in a short span of time, which couldn’t be managed thus far. Moving forward, we can expect the creation of a new form of aquaculture and revitalization of regions. Here, I would like to introduce genome editing in the context of aquaculture as well as activities towards its acceptance in society.