I would like here to introduce water’s edge border control strategies for epidemics in the coastal areas of western Kyushu in the Edo Period, as well as how foreign castaways received different treatment based on their origins; also, how the sick were quarantined on uninhabited islands (the Goto Islands in Nagasaki and Amakusa in Kumamoto). I would also like to examine issues regarding differences in treatment given to people who died from illness and how uninhabited islands are used today.